6992 people
- Spalding, Ann
- Spalding, Basil
- Spalding, Bernard
- Spalding, Electius
- Spalding, Enoch
- Spalding, Henry
- Spalding, William R.
- Spangler, George W.
- Sparedbeard, Thomas
- Sparling, Thomas
- Sparrow, Solomon
- Speake, Francis
- Speake, George
- Speake, Josias M.
- Speake, Samuel
- Speden, Robert
- Speiden, Robert
- Speiden, William
- Spence, John
- Spence, Mary
- Spencer
- Spencer
- Spencer, George
- Spilman, William C.
- Sprigg, Benjamin
- Sprigg, Richard
- Sprigg, Richard, Jr.
- Sprigg, Thomas
- Sryock, Samuel
- St. Clair, George
- St. Clair, Jane
- Stabler, William
- Stacey
- Stacey, Samuel
- Stacy
- Standley, George
- Standley, Jonathan
- Standley, Leah
- Standley, Rachel
- Stansberry, Lemuel
- Stanton, Richard
- Starke, Ann
- Starke, Thomas
- Starke, William I.
- Staughton, J. M.
- Steel, William
- Steele, Horatio N.
- Steiner, David
- Steiner, John
- Stelle, Pontius D.
